Eve Dawes is a Las Vegas-based fashion and beauty editor,…
Last Updated on March 20, 2026 by Eve Dawes
Exosomes and Growth Factors: Calecim Professional stem cell skin care might be the secret to ageless beauty. So of course I had to put it to the test!
Calecim Professional claims to be the best stem cell skin care and hair care on the market, so of course I had to put it to the test. In this Calecim Professional review, I’m sharing everything you need to know about their collection, which harnesses the world’s most powerful exosomes and growth factors through their patented PTT-6 complex, a high-concentration blend of stem cell proteins that drives real skin rejuvenation and cell regeneration. The results? Actually impressive. If you’re searching for the best anti-aging skincare and hair care products, keep reading. I tested the Calecim Professional Serum, Multi-Action Cream, Eye Contour Lifting Cream, and Advanced Hair System so you don’t have to. Here’s what truly sets them apart.
This Calecim Professional review contains affiliate links and gifted items which do not affect the price or my opinion.

What is PTT-6 used in Calecim Professional skincare
PTT-6® is a clinically proven combination of fibronectins, glycoproteins, collagen, and hyaluronic acid, that work synergistically to stimulate skin renewal at the cellular level. Dare I tell you where it’s from? It’s Cord Lining Conditioned Media ethically sourced from Red Deer (Stem cell derived Fibronectins, Glycoproteins, Albumin, Collagens, Hyaluronic Acid).
PTT-6® harnesses the body’s natural mechanisms of regeneration. It contains over 3,000 proteins, including growth factors, cytokines and exosomes that signal cells to regenerate. Calecim
When I say Calecim are wonder products, I mean it.

Where do the PTT-6 stem cells Calecim Professional uses come from
CALECIM Professional’s patented active ingredient PTT-6® is derived from the secretion of cord lining stem cells isolated from ethically sourced umbilical cord tissues of red deer which are farmed for their velvets in New Zealand. No deer is harmed in the process and they do not test on animals.
CALECIM’s unique source of extraction creates a really high potency PTT-6® which contains more than 3,000 active growth factors, cytokines and enormous amounts of exosomes in just one milliliter. Why does this matter? They work synergistically to accelerate daily skin repair, build up a healthy extracellular matrix and trigger skin cell production. It also helps your skin’s moisture and elastin production, triggers follicle cell production and reduces scalp inflammation which are often the cause of many types of hair loss.
Calecim Professional Serum review
Once you understand the ingredients and power of this serum there’s no going back! You can use the Calecim Professional Serum as a daily serum, but what I’d recommend is saving it for after dermarolling or microneedling. When you create microchannels in the skin, the serum can penetrate deeper and that’s where this makes a real difference, supporting collagen, elastin and skin healing. So after microneedling at home, I apply a couple of pipettes all over, and then focus on my areas that need the most help, under my eyes and scarring. It’s what makes an at-home treatment feel closer to a clinical one.
Calecim Professional Serum contains the highest concentration of their PTT-6® complex, designed to help skin regenerate and repair itself, improving texture, fine lines and pigmentation.
If you’re doing treatments at home and want that more clinical-level finish, these are the 2 steps that elevate it. Use my code EVE15 for 15% off this serum.
Calecim Professional multi-action cream review
Calecim Professional multi action cream works as both a day and night cream. It feels rich, hydrating, plumping and doesn’t pile under makeup. What makes it special is that it boosts collagen and elastin production, effectively lifting and firming your skin. It also repairs and restores all layers of skin for a healthy, supple, and radiant complexion. Lofty claims, but they have clinical trial results to back it up, and consider me impressed.

Ingredient-wise, besides having Calecim Professional PTT-6, it also has Linoleic acid which strengthens your skin barrier, and Tocopherol which is the most biologically active form of Vitamin E to help your skin to retain moisture. That to me is a winning formula when it comes to my specific skincare needs: hydration, aging well, and skin barrier strengthening.

Calecim Professional Review: Eye Contour Lifting Cream
I like to use products from the same collection as I find most are designed to work better synergistically. My eye lines are one of my main concerns when it comes to aging. Calecim Professional Eye Contour Cream also has PTT-6 as well as lots of other active ingredients including:
- Guarana extract to increase micro-circulation.
- Hesperidin and other lipopeptides to increase lymphatic circulation and improve the appearance of eye bags.
- Matrikines (peptides) that help degenerate blood-originated pigments responsible for dark circles.
- Cucumis, a natural anti-oxidant that soothes and provides a protective barrier.
- Niacinamide which increases fatty acid ceramide levels and also provides skin barrier protection.

I definitely feel like I haven’t had bags or dark circles while using this. Are my fine lines gone? No, but it’s not surgery, it’s a cream and they’re not getting worse. I think it’s incredibly hard to reverse the signs of aging, but if we can press pause, that’s pure gold!

Calecim Professional Advanced Hair System Review: Harnessing the Power of Stem Cells for Ultimate Skin and Hair Rejuvenation
If it’s hair loss or thinning you’re dealing with, have a look at Calecim Professional Advanced Hair System Hair Restoration Drops to boost density and help prevent shedding. These also have PTT-6® to stimulate your hair growth by activating the hair follicles and managing signs of inflammation that causes hair shedding. It also comes with an activator to help the product penetrate into your scalp deeper so it can work more effectively.

Their trials show:
- 0 reported side effects.
- 24% increase in follicle cell growth.
- 30x reduction in follicle inflammation
- 14% increase in the number of individual hairs on the scalp.
- 16% increase in hair shaft thickness.
- 15% in number of follicles per sq/cm of scalp.

What I like about these drops is that you only need to use them 2 x a week with the derma stamper (pictured below) whereas all of the other scalp drops I’ve tried you have to use 1-2x per day! Once you’re done with the 1st 6 weeks you can move into cycling between their maintenance phase where you just use them once a week. This article on hair science helps you decide whether or not Calecim Professional Advanced Hair System is right for you.

Save & score with Calecim Professional rewards club
If you want to earn points from shopping and referring people that you can redeem for free products you can sign up for their rewards program for free. Benefits include:
- Score full size products available for free.
- Product sampling.
- Discount vouchers.
- Exclusive online events.
- Get rewarded for referring a friend.
- Try the full range of products on them.
You also get a 10% off code when you sign up.

Shop Calecim skincare and haircare
These are the products I mentioned in this Calecim Professional review, as well as some of their other best sellers. Remember to use my discount code EVE15 to save some money.
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Eve Dawes is a Las Vegas-based fashion and beauty editor, content creator, luxury lifestyle blogger and founder of Best Luxury Handbags, the number one fashion blog in Las Vegas. With over 15 years of industry experience spanning professional performance, fashion styling, beauty formulation and fitness, Eve brings a level of genuine expertise to her content that goes well beyond standard blogging. Beauty and skincare expertise: Eve's beauty device coverage is backed by direct brand access that most independent reviewers don't have. She has had one-on-one training with Melanie Simon, founder of ZIIP Halo, giving her a deeper technical understanding of microcurrent and nanocurrent technology than any spec sheet can provide. She has had in-person education with CurrentBody directly and attended an exclusive Zoom masterclass with Dr Jason Diamond on the launch of his Metacine Eyelift. She is also the founder of Dawes Custom Cosmetics, a triple award-winning cruelty-free luxury cosmetics line - winning Best Custom-Blended Cosmetics Business USA and the LUX Customer Service Excellence Award Las Vegas, which gives her professional beauty formulation training that informs every product review she writes. Every recommendation on this site is based on genuine long-term personal testing, before and after photos included. Fashion and styling credentials: Originally from England, Eve trained as a ballerina at Central School of Ballet and London Studio Centre before touring internationally as a professional dancer with the Vienna Festival Ballet, in musicals, on TV, in music videos, theatres, casinos and cruise lines, and in films including Burlesque and Burt Wonderstone. This performance background gave her a unique eye for style, fit and how clothing moves on the body - which underpins everything she writes about fashion. She has collaborated with Revolve, Faviana, and designer Debbie Carroll, and has over 50 designer bags in her personal collection, making her designer handbag and luxury fashion coverage genuinely authoritative rather than aspirational. Fitness and wellness credentials: Eve is a NASM and REPS certified Personal Trainer, Sports Massage Therapist, Yoga and Spin instructor, a graduate of Premier International London, and a WBFF Professional Athlete who won her Pro card competing at the highest level of women's fitness competition. She is also Mrs. England World 2020 and Mrs. Nevada United States 2017, placing Top 15 at Mrs. United States, and was awarded the Nevada Community Service Award for two consecutive years. She studied the Art of Rhetoric and Persuasive Speech at Harvard. Press and media: Eve has been featured in Vogue, Rolling Stone, LA Times, Modern Luxury Magazine, Huffington Post, Oxygen Magazine, Iron Man Magazine, Strong Magazine, Fit and Firm Magazine, E!, BodyBuilding.com and Beast Games, among others. She has appeared in commercials, music videos and films, and previously worked as a content creator for Google Web Stories and is a Mediavine publisher. What you'll find on Best Luxury Handbags: Best Luxury Handbags covers luxury fashion and style, beauty devices and skincare, designer bags, travel and wellness - all through the lens of someone who has worn, tested and lived with the products she recommends. Nothing on this site is written from a press release.






